Research Tool
Anti-CtBP1 [CG14] Antibody
The technology
CtBP1 functions as a transcriptional compressor. CtBPs regulates epithelial to mesenchymal transition and cell metabolism. Due to the unavailability of commercial antibodies against human C-terminal-binding protein 1 (CtBP1), inventors at Virginia Commonwealth University have developed mouse monoclonal antibodies against this protein. Successful screening of the antibodies were performed by Western Blot (WB) analysis using CtBP1-His and the human ovarian cancer cell line SKOV3 as a source of material. The antibodies were also successfully tested in immunoprecipitation assays (IP), immunofluorescence cell staining (IHC), and chromatin immunoprecipitation assays (ChIP).
- Antigen/Gene or Protein Targets
- CtBP1 (does not cross-react with CtBP2)
- Reactivity
- Human
- Host
- Mouse
- Immunogen
- Full length protein C-terminal 6xHis-tag
- Subclass
- IgG2a kappa